KICK ‘Keto-flu,’ ‘Atkins-flu,’ and ‘adrenal fatigue’

Most of the symptoms that the internet community attributes to ‘Keto-flu,’ ‘Atkins-flu,’ and ‘adrenal fatigue’, insomnia, anxiety, and slow recovery after exercise can be cured by a modest daily supplement of one essential nutrient – sodium (aka salt).

There is no science linking carbohydrate restriction and/or nutritional ketosis to impaired adrenal function (i.e., inadequate cortisol or adrenaline production).

To avoid confusion, we need to differentiate between ‘sodium depletion’ – which triggers the renin/aldosterole pathwaythat reduces sodium excretion – and simple dehydration. Dehydration triggers thirst, which stimulates water consumption. But water consumption alone cannot reverse the symptoms of sodium depletion. Without enough sodium in the body, no amount of water intake can maintain normal volume in the circulation. Dehydration by itself tends to be self-correcting. Sodium depletion are symptoms less specific.

Sodium – Essential But Still Controversial

Sodium.png

Sodium has been recognized for thousands of years as an essential mineral for human well-being and function, but the optimum level of intake for humans remains highly controversial. Sodium intake has been linked to increased blood pressure in about 25% of the general population, and given the strong association between hypertension and cardiovascular disease, the assumption has been that we all should consume less sodium to reduce our heart-attack risk. In other words, we are all told to limit our salt intakes because this is assumed to be benign for most of us and life-saving for the minority with what is called ‘salt-sensitive hypertension.’

We must question this one-size-fits-all recommendation. Why? Because no one has bothered to do the obvious study in which people with normal blood pressure restrict their salt intakes for years at a time to see if this improves their overall health, or at least does them no harm.

The Salt/Sodium Adrenal-Hormone Connection

Eat no salt for more than a few weeks and you die. Don’t eat quite enough salt long term and you will develop symptoms that are the same as those described for ‘adrenal fatigue’, such as weakness, fatigue or low energy, headache, nausea, vomiting, muscle cramps or spasms, confusion and irritability.

Sodium is an essential mineral found in your blood, specifically in your serum, and in the extra-cellular fluid that surrounds all of the body’s cells. Its level in the blood is guarded by the actions of both your kidneys and adrenal glands. Eat too much salt and your kidneys accelerate its excretion.

Eat too little and your adrenals make a hormone called aldosterone that causes your kidneys to conserve sodium, but in doing so they are physiologically obligated to simultaneously waste potassium. Wasting too much potassium is not good because your muscles, heart, and nerves need to contain the right amount of potassium to work properly.

The reduced amount of sodium available in the circulation that triggers the adrenal gland to increase production of aldosterone also increases adrenal production of the stress hormone cortisol and the fight-or-flight hormone adrenaline. Increased cortisol and adrenaline levels are stress hormones that are potent impediments of healthy sleep.

Bottom line: salt, potassium, adrenaline, and cortisol are intimately connected; there is a clear relationship between inadequate dietary sodium and the purported signs of ‘adrenal fatigue.’

How Nutritional Ketosis Affects Your Sodium Needs

With adaptation to nutritional ketosis over a number of weeks, many basic functions of the body undergo profound changes:

  • Fat (and ketones made from fat) replaces glucose as the primary fuel
  • Sensitivity to multiple hormones, including insulin and thyroid hormones, improves
  • The kidneys switch from retaining sodium to rapidly excreting it, (normal sodium metabolism with nutritional ketosis).

For those who are prone to retain sodium (e.g., causing bloating, high blood pressure, congestive heart failure, edema/ankle swelling), this accelerated sodium excretion with nutritional ketosis is a blessing. But once any excess sodium and water have been cleared from the body in the first few weeks of a ketogenic diet, a new balance of sodium intake to sodium excretion then has to occur so that adequate blood circulation (aka, circulating volume) can be maintained. However if, in this keto-adapted state, dietary sodium is restricted, your brain and kidneys signal your adrenals to increase aldosterone and cortisol. What this means is that a combination of nutritional ketosis plus salt restriction leads to adrenal stress.

   Nutritional ketosis + salt restriction = adrenal stress

Research Linking Ketogenic Diets to Adrenal Stress

Despite the hundreds of published studies of humans on ketogenic diets lasting as long as 2 years, there is no credible scientific evidence for adrenal damage or fatigue.

Research Showing Normal Blood Cortisol During Ketogenic Diets

There is just one paper showing that serum cortisol levels remained normal in 12 men given a well-formulated ketogenic diet for 6 weeks (Volek, 2002).

Why It Is Safe to Recommend Adding Salt to a Ketogenic Diet

First,since nutritional ketosis accelerates sodium excretion by the kidneys, whatever risk might be associated with too much sodium at any one level of salt intake would be less during ketosis than when eating a high carb intake. Stated another way, a high carbohydrate intake suppresses the body’s natural ability to excrete sodium and thus reduces a person’s ‘salt tolerance.’ Insulin is known to be involved in renal sodium metabolism.

The second important point is found in a recently published study that threatens to derail the whole anti-salt crusade. An international group of scientists collected urine samples from over 100,000 adults in 17 countries and then observed their health status for 4 years (O’Donnell 2014). They reported that people consuming less than 4 grams of sodium per day had a sharply increasing risk of death, almost doubling when they got down to 2 grams/day of sodium. In contrast, with higher sodium intakes, the risk of death rose very slowly beginning with intakes above 6 grams/day.  For example, as shown in the diagram below, mortality risk was increased by only 15% at 8 grams/day.

See the Chart: ** Estimated sodium excretion and risk of death from any cause

Blog - Sept. 27 chart.png

Optimum Sodium Intake During Nutritional Ketosis

Virta’s recommended sodium intake for most people during a well-formulated ketogenic diet is based upon the amount needed to avoid the symptoms of ‘Atkins flu’ or ‘adrenal fatigue’ is 5 grams per day (3 grams in your food, 2 grams from broth/bouillon).

There are still variations between individuals that necessarily modify this advice.

  • People with high blood pressure or fluid retention that persists after keto-adaptation, and particularly if they are taking a diuretic medication, should not increase their sodium intake above 3 grams per day until these symptoms are resolved and the diuretic medication stopped.
  • People routinely taking NSAID medications like ibuprofen (Motrin, Advil) or (Aleve, Naprosyn) are more ‘sodium sensitive’ because these drugs block salt excretion by the kidneys and raise blood pressure.
  • Heavy physical exercise in the heat will cause increased sodium loss in sweat, which can increase one’s daily sodium requirement above the 5-gram level.

And finally, as always, it is important to distinguish between grams of sodium and grams of salt.

    Salt and sodium are not the same.

    1 teaspoon of salt = 5 grams of salt = 2.3 grams of sodium (the rest is chloride)

High quality studies published by Virta and others continues to lead us to the scientifically correct view: nutritional ketosis is good for you. In particular, given the emerging view of ketones as both a fuel and beneficial epigenetic signal (arising from nongenetic influences on gene expression), there is unique therapeutic value to nutritional ketosis. And all that is needed to capture these benefits is to supply the  daily salt intake required to maintain an optimum balance of sodium and potassium in the body.

    Ask yourself this question: if nutritional ketosis has been shown to markedly increase my defense against oxidative stress, and it also makes mice and worms live 13-26% longer, why would I give up these advantages just so I could eat sugar and refined carbs?

This Post has been condensed from: Sodium, Nutritional Ketosis, and Adrenal Function

By Stephen Phinney, MD, PhD, Jeff Volek, PhD, RD, Citations for scientific studies.

https://blog.virtahealth.com/sodium-nutritional-ketosis-keto-flu-adrenal-function/

I invite you to Follow my Blog, Facebook or be added to my email distribution list. My focus is to maximize my physical performance and mental clarity, body composition, and most importantly overall health with a wholesome diet and exercise. 

I will bring you compelling articles on Ketogenic and GAPS diets, the Super Slow High-Intensity Exercise Program and supplements.

 To follow my Blog, please click the Follow button to receive an email when the next posting is available. Hint: You may have to click the Accept and Close button before follow is available.

I thrive on feedback. Please let me know you are interested in the content by clicking Like, Commenting or sending me a message or email about the Post.

If you wish to contact me by Email, please email lpolstra@bell.net using this form.

May you Live Long Healthy.

Yours truly,

Lydia Polstra

Email: lpolstra@bell.net

Facebook: https://www.facebook.com/2healthyhabits/

Blog: https://2healthyhabits.wordpress.com

Disclaimer: The content of this email or Post is not intended for the treatment or prevention of disease, nor as a substitute for medical treatment, nor as an alternative to medical advice. Use of recommendations is at the choice and risk of the reader.

Managing Potassium and Sodium On a Ketogenic Diet

A well-formulated ketogenic diet (WFKD) requires real food choices and preparation to maintain an optimum potassium intake.

Blog - Sept. 20 picture.

The sodium and potassium management by the kidneys and the changes in sodium handling during nutritional ketosis is makes this especially important.

Potassium and Mortality in the Balance

Potassium is the positively charged ion (aka electrolyte) that is predominate in the fluid inside all of the body’s cells, while sodium plays a matching role in the fluid surrounding our cells – including blood plasma. Keeping the two of them in balance is involves multiple hormones and organs, particularly the kidneys.

In order for nerves and muscles to function, the concentrations of positively charged potassium (K+) and sodium (Na+) have to be essentially equal across the cell membranes. If either this balance, or the in-and-out flow of these two electrolytes is impaired, nerves and muscles don’t work properly, endangering health and even life itself.

Because part of sodium’s role in the plasma is to maintain adequate circulation, it has been well characterized as necessary for normal blood flow. And in the case of high blood pressure, it is tempting to conclude that one just needs to restrict sodium intake to get it to come back down. While there is some truth to this (for people with salt-sensitive hypertension), for most people with high blood pressure, it involves the appropriate balance between these two electrolytes rather than a focus on the intake of sodium in isolation.

Recently, large studies have measured the actual amounts of sodium in a person’s urine. The most definitive results to date are from the massive international PURE study reported by O’Donnell et al. In this study, they collected urine from 102,000 people in 17 countries and then monitored health and mortality for 4 years. The lowest mortality was seen in people consuming 5 grams per day, which is about twice the current US recommended guideline for healthy adults. For sodium intakes substantially above or below this value, the associated mortality rates rise, generating a U-shaped curve.

See The Estimated Sodium Excretion chart below. *

Blog - Sept 20 chart 1

But the urinary potassium data from the PURE Study (See The Roles of Vegetables and Broth in Reducing Risk of Death chart below) tell a very different story. While low levels of potassium excretion are clearly associated with increased mortality risk, increasing levels in the urine up to 3-4 grams per day correlate with reduced risk. And in particular, the associated mortality at 1 gram per day is about double that seen at 3 grams per day. For this reason, we recommend incorporating real foods into a WFKD providing 3-4 grams per day of potassium.

See the Roles Of Vegetables And Broth In Reducing Risk Of Death chart below **

Blog - Sept 20 chart 2

The Relationship Between Sodium and Potassium Intakes and Urinary Excretion

Almost all of the sodium we eat gets absorbed, and then about 90% of that comes out in our urine. Therefore, urinary sodium is an accurate reflection of our dietary intake.

However, this relationship between dietary intake and urinary output is not quite as good for potassium. In most people, about 75% of dietary potassium is excreted in the urine. Thus, in the studies linking urinary potassium excretion to health a correction factor of about 1.3 should be applied. This means that in order to have 2 grams of potassium come out in the urine, one would need to consume 2.6 grams in the diet, and similarly to have 3 grams in the urine would require about 4 grams of dietary intake.

Practical Health Implications of Dietary Potassium

An important point to note here is that processing of meat to create luncheon meat, hot dogs, or bacon removes much of the potassium originally associated with that protein source and therefore should be restricted. In addition, if unprocessed protein sources are boiled or stewed, some of the potassium they contain comes out in the broth. Thus they should be prepared and served such that the broth or sauce is consumed to get the full benefit of their electrolytes and minerals.

Official Dietary Potassium Guidelines

The great majority of the population eats far less than the current estimated Adequate Intake value of 4.7 grams.

The reason it is only an estimate is because when dietary sodium is restricted, the kidneys tend to excrete more potassium to maintain the balance. This process is regulated by a series of hormones, with the main one being the stress hormone aldosterone. On average a sodium-restricted diet given to people with normal blood pressure increases this stress hormone more than 3-fold.

Getting Enough Potassium with a WFKD

From what we currently know about potassium needs for someone getting adequate sodium on a WFKD, 3 to 4 grams per day, appears to be an appropriate target to provide the necessary amount of potassium for health-related benefits.

This is an amount that is achievable with real foods.To begin, the right choices of protein that are prepared correctly will provide the first gram. On average, non-starchy vegetables that are consumed raw, sautéed or steamed contain about 200 mg per standard serving, so 4-5 servings of vegetables per day will provide the second gram. Nuts and seeds vary in their potassium content but range from 100-300 mg per ounce (oz), so 2 oz per day moves the scale closer to the 3 g per day optimum target.

Broth

The amount of potassium in home-made broth will vary depending upon how much meat remains on the bones used to prepare the broth. Typically, a pound of chicken carcass or meaty beef bones used to make a quart of broth will contain 200-300 mg of potassium per cup.

Technical Information on the Regulation of Electrolyte Balance

It is known that both total fasting and a ketogenic diet lead to an accelerated sodium excretion that increases water and salt loss through the urine. If this lost sodium is not replaced, the kidneys will reabsorb sodium. This process comes at the price of increased potassium excretion.

With consistent loss of potassium and/or chronically low intake of potassium the body will attempt to correct via the release of intracellular potassium from skeletal muscle.

It is clear that maintaining sufficient sodium and potassium intakes from the diet serves a number of important functions: potential mitigation of risk for cardiac events, preservation of plasma volume and muscle mass, and prevention or reduction of symptoms of the ‘keto- flu’.

The fail-safe endocrine system responsible for the tight regulation of electrolytes is commonly referred to as the renin-angiotensin-aldosterone system (RAAS). When plasma sodium levels are low (an intake of less than 3 grams per day), when blood potassium levels are significantly elevated (hyperkalemia), or when there is a notable reduction in blood pressure, RAAS is activated.

The cost for frequent RAAS activation is increased oxidative stress, increased vascular damage, measurable dyslipidemia * and potential sleep and mood disturbances.

Dyslipidemia * is elevation of plasma cholesterol, triglycerides (TGs), or both, or a low HDL cholesterol level that contributes to the development of atherosclerosis. Sourcehttps://www.merckmanuals.com/en-ca/professional/endocrine-and-metabolic-disorders/lipid-disorders/dyslipidemia

This compensatory activity of RAAS as well as increased sympathetic nervous system activity that together work to maintain electrolyte levels helps explain why we typically do not see a large decrease in blood pressure when sodium is restricted in most patients. In those who do not have salt-sensitive hypertension, these systems appear to adjust to dietary intake and manipulate sodium, potassium and fluid levels in order to maintain a person’s blood pressure.

The important role of potassium in muscle function and sodium in maintaining plasma volume are added considerations for individuals who exercise or engage in activity that results in a large volume of sweat loss. Due to the loss of Na+ and K+ in sweat, these circumstances may require additional electrolyte replacement in order to maintain performance, especially for those following a ketogenic way of eating. A good rule of thumb is about ½ tsp of salt 30 minutes prior to exercise and if exercise is performed at a relatively-high intensity in a hot environment, an additional ½ tsp of salt each hour may be warranted.

 For better health and well-being on a WFKD consume the recommended amounts of the electrolytes, sodium 3-5 g and potassium 3-4 g per day, will help support overall health as well as the success and sustainability of nutritional ketosis.

Talk to your doctor about your sodium and potassium needs, if you are taking a diuretic medication (aka, a water pill), if you have high blood pressure, if you have any impairment in kidney function, or if you have limited heart function (such as congestive heart failure).

This Post has been condensed fromThe Importance of Managing Potassium and Sodium as Part of a Ketogenic Diet by Stephen Phinney, MD, PhD, Jeff Volek, PhD, RD. Please see the original post for the scientific citations.

https://blog.virtahealth.com/potassium-sodium-ketogenic-diet/

I invite you to Follow my Blog, Facebook or be added to my email distribution list. My focus is to maximize my physical performance and mental clarity, body composition, and most importantly overall health with a wholesome diet and exercise.

I will bring you compelling articles on Ketogenic and GAPS diets, the Super Slow High-Intensity Exercise Program and supplements.

To follow my Blog, please click the Follow button to receive an email when the next posting is available. Hint: You may have to click the Accept and Close button before follow is available.

I thrive on feedback. Please let me know you are interested in the content by clicking Like, Commenting or sending me a message or email about the Post.

If you wish to contact me by Email, please email lpolstra@bell.net using this form.

May you Live Long Healthy.

Yours truly,

Lydia Polstra

Email: lpolstra@bell.net

Facebook: https://www.facebook.com/2healthyhabits/

Blog: https://2healthyhabits.wordpress.com

Disclaimer: The content of this email or Post is not intended for the treatment or prevention of disease, nor as a substitute for medical treatment, nor as an alternative to medical advice. Use of recommendations is at the choice and risk of the reader.

Managing Cancer as a Metabolic Disease Part Two

Last week, in Managing Cancer as a Metabolic Disease Part One, we learned that,

genetic mutations are not the primary cause of cancer but are, rather, a downstream effect of the defective energy metabolism. As long as your mitochondria remain healthy and functional, your chances of developing cancer are slim!”

Here is the link to that Blog Post https://2healthyhabits.wordpress.com/2019/09/06/managing-cancer-as-a-metabolic-disease-part-one/

This week we will continue with more success stories.

Mayo Clinic Asks Long-Term Physician Cancer Survivor: ‘Just What Are You Doing?’

Dr. Bomar Herrin, 58, worked out regularly. During a workout he felt a snap near his right shoulder.

A biopsy revealed it was caused by a plasmacytoma, or a cluster of cancerous plasma cells. Plasma cells are a type of white blood cell, and when they become abnormal they are called myeloma. Myeloma cells in several parts of the body are called multiple myeloma. While Herrin had radiation to treat the plasmacytoma in his arm, a PET scan revealed lesions on his spine, sacrum and ribs, which indicated that his cancer might have spread.

Strongly motivated to find a way to halt the progression of his disease, he embarked on a different path: metabolic therapy. That was eight years ago. For eight years, Herrin has been following a ketogenic diet and fasting regularly. He recently reported to Seyfried that his cancer load and inflammation markers are down.

In March 2017, his kappa/lambda ratio was normal for the first time – a measure of multiple myeloma activity. And he reports: “At the Mayo Clinic, I am now being asked to describe just what I am doing!”

Colon Cancer Patient Says ‘No’ to Standard Care and ‘Yes’ to the Ketogenic Diet — Four Years Later She Remains Cancer-Free

A gentleman who learned about Seyfried and metabolic therapy from an interview just four days after his wife had surgery for colon cancer. A 3-centimeter malignant section of her colon was removed, as well as 12 adjacent lymph nodes. Eight of them were cancerous.

Both this gentleman and his wife, Barb, had listened intently to his interview. That turned out to be a pivotal event in his wife’s health journey. Shortly after her surgery, his wife was advised to commence the standard chemo regimen. Instead, she decided to start the ketogenic diet. Four years later, she continues to follow her ketogenic diet.  During the last four years, her six-month tests have all been cancer-free!

Blog Sept. 4 picture

Dr. Thomas Seyfried

5 Powerful Steps to Minimize Your Cancer Risk

  • Switch over to a cyclical ketogenic diet and then intermittent feasting and fasting (You’ll find the exact steps in Mercola’s book “Fat for Fuel”)
  • Avoid pesticides, herbicides, genetically engineered and factory farmed foods (choose organic, locally grown wholefoods whenever possible)
  • Move more and exercise regularly (simply sitting less can make a profound difference in your health)
  • Get regular sun exposure and maintain healthy vitamin D serum levels (>60 ng/ml)
  • Detox your body with regular full spectrum infrared sauna sessions

Success Stories Pour In – What Metabolic Therapy Can Potentially Do for End-Stage Cancer Patients

Dr. Abdul Slocum, a physician from Turkey, sees many end-stage cancer patients in his clinic, ChemoThermia Oncology Center. A significant number of his patients have pancreatic cancer.

Pancreatic cancer has one of the worst prognoses of any cancer with over 90 percent of its victims dead within five years.

Most patients are diagnosed with the disease in its advanced stages. When a patient discovers he has stage 4 pancreatic adenocarcinoma, his life expectancy is about six months. If liver metastasis has occurred, he may live for only weeks.

Many of Slocum’s patients have failed traditional therapies and some have even been sent home to die. When they enter his clinic, patients are immediately placed on a ketogenic diet and remain on it throughout their treatment. Here’s what’s most noteworthy about Slocum’s approach:

  • Treatment protocols are non-toxic and utilize practices based on metabolic therapy
  • Any chemotherapy agents used are applied in the lowest possible dose to minimize harm to the body (and keep it an “approved” treatment)
  • Patients experience a high quality of life during treatment, unlike the discomfort and toxic side effects that typically accompany conventional treatments

Slocum and his team are seeing remarkable success with metabolic therapy in a broad range of advanced stage cancers including those involving the pancreas, lung, breasts, ovaries and stomach.

Could Metabolic Therapy Be Your Very Best Chance of Recovery If You Were Diagnosed With Cancer?

Slocum isn’t the only cancer specialist seeing positive results. Dr. Jean-Pierre Spinosa is also reporting exciting results with metabolic therapy with patients in his practice in Switzerland:

  • Two patients with metastatic breast cancer are still completely free of cancer
  • A patient with metastatic prostate cancer is stable with PSA remaining at 7
  • A patient with leiomyosarcoma (an aggressive type of soft tissue sarcoma) is stable
  • A patient with inoperable grade 4 glioblastoma is stabilized on metabolic therapy

Of course, he and his patients are very encouraged by these results. However, metabolic therapy isn’t a magic wand. It won’t – and doesn’t – save everyone’s life. Typically, a majority of the clinics following this alternative protocol see patients at the end of their journey, typically when traditional treatments have failed. Unfortunately, a certain percentage of patients aren’t going to survive, no matter what.

But if patients can get through this metabolic protocol, the median survival can increase 400 percent and their quality of life can be drastically improved.That’s incredible!And imagine the potential outcome if clinics like these could treat more patients who are newly diagnosed and haven’t yet been exposed to toxic and health-harming treatments? I believe that metabolic therapy creates for you, your family or loved ones, the very best chance for recovery from this devastating disease.

If You’re Supporting Traditional Cancer Causes, Do You Know Where Your Money Goes?

Did you know that Breast Cancer Awareness Month was launched by Astra Zeneca, a pharmaceutical company that sells both cancer treatments AND toxic, carcinogenic pesticides? Astra Zeneca potentially profits from both.

If you support activities that include “racing for the cure,” your money goes to Komen. In 2016, Komen had an annual revenue of over $200 million, they awarded 103 grants totalling $33 million – about 16.5 percent. Only 4 percent of grant money was dedicated to prevention!

In 2017 the Tampa Bay Times and The Center for Investigative Reporting compiled this exhaustive list based on federal tax filings for the past 10 years. They solicited donations in excess of $1.35 billion (for the entire list of 50 charities). At least twelve cancer foundations.Here is the link https://smartasset.com/mortgage/the-50-worst-charities-in-america-how-to-keep-from-being-scammed

Less than 10 percent actually went to help individuals in need or for research. Your donation supports research and therapies that reinforce the failures of chemotherapy, radiation and surgery.

Important Cutting Edge Metabolic Therapies That Address the True Cause of Cancer: Defective Mitochondria

Emerging evidence shows that cancer is primarily a metabolic disease involving disturbances in energy production through respiration and fermentation in the cells. Research shows that cancer is suppressed when the nucleus from a tumor cell is transferred to cytoplasm of normal cells with normal mitochondria.

Blog Sept. 13 Mitochondria

Defective (empty GBM) mitochondria within the cell can’t produce energy normally

It is the normal mitochondria that suppress cancer growth.This finding alone is enough to cast serious doubt on the genetic theory of cancer. The disturbances in tumor cell energy metabolism can be linked to abnormalities in the structure and function of the mitochondria.

Seyfried’s research has shown that cancer growth and progression can be managed following a whole-body transition from fermentable metabolites, such as glucose and glutamine, to respiratory metabolites, primarily ketone bodies that are formed when you follow a ketogenic diet.This transition reduces tumor vascularity and inflammation while enhancing tumor cell death.

A novel “press-pulse” therapeutic strategy is in development for the non-toxic metabolic management of cancer. The conclusions:Optimization of dosing, timing, and scheduling of the press-pulse therapeutic strategy will facilitate the eradication of tumor cells with minimal patient toxicity. This therapeutic strategy can be used as a framework for the design of clinical trials for the non-toxic management of mostcancers.To read the study please copy and past this link into your address bar https://www.ncbi.nlm.nih.gov/pubmed/28250801

Seyfried’s lab is currently exploring a number of metabolic therapies in a metastatic mouse model, including the combination of the following:

Ketogenic diet *

Glycolytic inhibitors

Oxygen therapy

Glutamine inhibitors

Exogenous ketones

Other metabolic targeting therapies

The goal of this advanced research is to develop a non-toxic diet/drug therapeutic treatment that can resolve both primary tumor growth AND secondary tumor metastatic lesions in a range of preclinical models of cancer.

To learn more about the Ketogenic diet * read, How Do I Do the Ketogenic Diet? https://wordpress.com/post/2healthyhabits.wordpress.com/494

These Posts have been condensed from Dr. Mercola’s original post,https://articles.mercola.com/sites/articles/archive/2017/08/02/metabolic-therapy-for-cancer.aspx

I invite you to Follow my Blog, Facebook or be added to my email distribution list. My focus is to maximize my physical performance and mental clarity, body composition, and most importantly overall health with a wholesome diet and exercise.

I will bring you compelling articles on Ketogenic and GAPS diets, the Super Slow High-Intensity Exercise Program and supplements.

To follow my Blog, please click the Follow button to receive an email when the next posting is available. Hint: You may have to click the Accept and Close button before follow is available.

I thrive on feedback. Please let me know you are interested in the content by clicking Like, Commenting or sending me a message or email about the Post.

If you wish to contact me by Email, please email lpolstra@bell.net using this form.

May you Live Long Healthy.

Yours truly,

Lydia Polstra

Email: lpolstra@bell.net

Facebook: https://www.facebook.com/2healthyhabits/

Blog: https://2healthyhabits.wordpress.com

Disclaimer: The content of this email or Post is not intended for the treatment or prevention of disease, nor as a substitute for medical treatment, nor as an alternative to medical advice. Use of recommendations is at the choice and risk of the reader.

Managing Cancer as a Metabolic Disease Part One

Groundbreaking research reveals cancer is primarily a metabolic disease that need not be a death sentence.

Metabolic therapy, which includes a ketogenic diet, has been shown to prevent and treat many cancers, including “incurable” late-stage cancers.

With this powerful nutritional strategy, the unnecessary deaths from cancer could be radically reduced.

But first, let’s take a look at what’s standing in the way.

The conventional medical community is so attached to the flawed genetic theory of cancer that they fail to use new science exposing the mitochondria dysfunction that is evident in almost all cancers.

If you are diagnosed today with cancer, you basically receive the same dated ineffective strategy that has failed for over 50 years! Conventional oncologists still rely on the “slash, burn and poison” protocol: surgery, radiation and toxic chemotherapy.

Chemotherapy was developed after World War II from a derivative of mustard gas. Mustard gas and other chemotherapies are powerful carcinogens. These conventional treatments simply aren’t working.

Even the newer era of “targeted immunotherapies” have been a dismal failure. Indeed, the probability of dying from these therapies is greater than the probability of living slightly longer. Yet we are spending billions on new and increasingly more expensive cancer drugs that have marginal efficacy at best.

Established oncology clings to the failed system based on the gene theory and tries to generate hope for new cancer drugs that continue to fail us. A vast pharmaceutical system supports the current cancer ideology. When you’re treated for cancer in the U.S. and many other developed nations, these established therapies are your ONLY options. Your oncologist must treat you within the standard protocol of slash, burn and poison!

Effective non-toxic treatments are available. Non-patentable therapies can’t get the billion-dollar backing to fund the type of studies that would win approval from the oncology community.

What if you could feel empowered to prevent and treat cancer — without toxic, health-damaging treatments?

The National Cancer Institute and the academic and pharmaceutical cancer industries are locked into an old school of thought: Cancer is a genetic disease. Because they’re not willing to look at alternative causes for cancer (there’s no shortage of scientific evidence to prove cancer isn’t a genetic disease) it’s nearly impossible to advance innovative therapies for cancer management and prevention.

The good news is, there are pioneers out there who are working tirelessly to develop treatment protocols that can radically address, prevent and treat most cases of cancer.

Meet THE Game Changer in the World of Cancer: Thomas Seyfried

Blog Sept. 4 picture

Thomas Seyfried is a professor, researcher and author at Boston College. In 2012 Seyfried wrote the book on how cancer needs to be treated in principle, “Cancer as a Metabolic Disease: On the Origin, Management and Treatment of Cancer.” This is the gold standard medical textbook for alternative oncologists and a savvy public. It is available on Amazon https://www.amazon.ca/Cancer-Metabolic-Disease-Management-Prevention/dp/0470584920

But unless you have training in biochemistry, you may want to start with Travis Christofferson’s best-selling book, “Tripping over the Truth: How the Metabolic Theory of Cancer Is Overturning One of Medicine’s Most Entrenched Paradigms.” Christofferson’s book is a needed step to understanding the details of Seyfried’s pioneering work. It is available on Amazon https://www.amazon.com/Tripping-over-Truth-Overturning-Entrenched/dp/1603587292

Seyfried has a distinguished background. He was a postdoctoral fellow in the department of neurology at the Yale University School of Medicine and then served on the faculty as an assistant professor in neurology. Throughout his long career, he’s received many awards and honors from organizations such as the National Institutes of Health, the American Society for Neurochemistry and the Ketogenic Diet Special Interest Group of the American Epilepsy Society.

He recently received the Distinguished Alumni Award from the University of New England, and a lifetime achievement award from the Academy of Comprehensive Integrative Medicine.

He presently serves on several editorial boards, including those for Nutrition and Metabolism, Neurochemical Research, the Journal of Lipid Research and ASN Neuro, where he is a senior editor. In total, Seyfried also has over 170 peer-reviewed publications in the scientific literature.

How Seyfried’s Metabolic Theory of Cancer Differs From the Genetic Model of Cancer

Keep in mind, the established dogma that cancer is a genetic disease rules everything — from the research that receives funding to how an oncologist treats you in the U.S. and other developed nations. This dogma is what fuels the entire cancer industry. However, Seyfried disagrees. He and others have been able to advance the theory that cancer is primarily the result of defective energy metabolism in, and damage to, the cells’ mitochondria.

Simply put, genetic mutations are not the primary cause of cancer but are, rather, a downstream effect of the defective energy metabolism. As long as your mitochondria remain healthy and functional, your chances of developing cancer are slim!

Seyfried is one of the pioneers in the application of nutritional ketosis for cancer, a therapy that stems from the work of Dr. Otto Warburg, one of the most brilliant biochemists of the 20th century. Warburg, a personal friend of Albert Einstein, received the Nobel Prize in Physiology or Medicine in 1931 for how cells obtain energy from respiration. He was even nominated for two additional Nobel’s.

His life’s mission was to find a cure for cancer. However, the findings from his work on cancer’s cause and cellular processes were largely ignored and ridiculed by the oncology research community because they were considered too simple and didn’t fit the genetic model.

Seyfried has followed in Warburg’s scientific footsteps. He conducts important research at Boston College to advance the metabolic theory of cancer and the crucial role nutritional ketosis plays in both prevention and treatment. Let’s learn more about how Seyfried’s important work is saving cancer patients’ lives — and what that might mean for you, too, if you develop cancer.

Meet Travis Christofferson

He is the author of one of the most profound books ever written about cancer: “Tripping Over the Truth.” In his book, Christofferson demonstrates in no uncertain terms why the conventional approach to cancer treatment is fatally flawed.

His book is available through Amazon https://www.amazon.com/Tripping-over-Truth-Overturning-Entrenched/dp/1603587292

Describing the journey from discovery to today’s applications in very readable terms, he traces the development of metabolic therapy from Dr. Otto Warburg’s early work to Thomas Seyfried’s groundbreaking advancements. In 2013, Christofferson set up the nonprofit Single Cause Single Cure Foundation to support the research and clinical application of metabolic therapies for cancer patients. To learn more please copy and past this link into your address bar https://careoncology.com/

When this Blogger contacted Christofferson he told me about the COC Protocol which was developed to have wide-ranging anticancer activity with the potential to benefit patients with cancer of any stage, or type. Abundant existing data supports the individual use of each of the COC protocol medications in cancers of all types (including solid tumours and blood cancers).

Cancer Victim With Inoperable Brain Tumor and Just Months to Live Embraces the Ketogenic Diet

When Pablo Kelly, aged 25, started having migraines in 2013. Soon after nearly collapsing at work and experiencing a drooping of one side of his mouth, and then seizures, he feared something serious was happening to him. Pablo learned he had inoperable stage 4 glioblastoma multiforme, a deadly form of brain cancer. And he was told he had just months to live.

When doctors offered him radiation treatments and chemotherapy, he did the math and realized the survival statistics for his age were about 3 percent, and that was with up to 15 months of chemotherapy.

Without chemotherapy, he was told he had six to nine months. Pablo made a bold decision that went against his doctors’ beliefs and advice. He decided to decline all treatments and, instead, follow a ketogenic diet. His new eating plan excluded processed foods, refined sugars, starches, breads, grains and even root vegetables. Pablo felt he had nothing to lose by making a drastic change in his eating habits. Two years later, CT scans show no growth of his tumor.

He attributes his unusual success to his special diet, supplements and natural anti-inflammatories. Regularly, he fasts and restricts his calories. Pablo is convinced that the ketones his body produces during ketosis supply fuel to his healthy cells, and the lack of glucose helps starve and stabilize his tumor.

And here’s an exciting last minute update to his story: Pablo just wrote to Seyfried to tell him that, while his brain tumor was originally considered inoperable, it became operable after two years on ketogenic metabolic therapy. He recently had brain surgery and is currently doing very well!

This is Post is Managing Cancer as a Metabolic Disease Part One

Part Two with more success stories will follow next week.

These Posts have been condensed from Dr. Mercola’s original post,https://articles.mercola.com/sites/articles/archive/2017/08/02/metabolic-therapy-for-cancer.aspx

I invite you to Follow my Blog, Facebook or be added to my email distribution list. My focus is to maximize my physical performance and mental clarity, body composition, and most importantly overall health with a wholesome diet and exercise.

I will bring you compelling articles on Ketogenic and GAPS diets, the Super Slow High-Intensity Exercise Program and supplements.

To follow my Blog, please click the Follow button to receive an email when the next posting is available. Hint: You may have to click the Accept and Close button before follow is available.

I thrive on feedback. Please let me know you are interested in the content by clicking Like, Commenting or sending me a message or email about the Post.

If you wish to contact me by Email, please email lpolstra@bell.net using this form.

May you Live Long Healthy.

Yours truly,

Lydia Polstra

Email: lpolstra@bell.net

Facebook: https://www.facebook.com/2healthyhabits/

Blog: https://2healthyhabits.wordpress.com

Disclaimer: The content of this email or Post is not intended for the treatment or prevention of disease, nor as a substitute for medical treatment, nor as an alternative to medical advice. Use of recommendations is at the choice and risk of the reader.